Macromolecular X-ray Crystallography Facility
The Macromolecular X-ray Crystallography Facility houses high-throughput crystallization robotics, a state-of-the-art
rotating anode/imaging plate X-ray crystallography data collection suite, a cryosystem, and a collection of Apple, SGI and
Linux computer workstations and software for crystallographic computations, molecular visualization, and model building.
Recently, robotics have been added to the facility that allow high-throughput crystallization screening.
 The facility is supervised by Professors Harry Noller, Bill Scott, Melissa Jurica and Seth Rubin (Dept. of MCD
Biology, Dept. of Chemistry and Biochemistry). UCSC scientists have used the facility to investigate the structure
of the ribosome, catalytic RNA ("ribozymes"), the spliceosome, and protein structures relevant to cell cycle
regulation. Users of the facility also collaborate with the Lawrence Berkeley National Laboratory's Advanced Light
Source synchrotron radiation facility and the Stanford Synchrotron Light Source.
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