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MACROMOLECULAR X-RAY CRYSTALLOGRAPHY FACILITY
The Macromolecular X-ray Crystallography Facility houses
high-throughput crystallization robotics, a state-of-the-art rotating anode/imaging
plate X-ray crystallography data collection suite, a cryosystem, and a collection
of Apple, SGI and Linux computer workstations and software for crystallographic
computations, molecular visualization, and model building.
The facility is supervised by
Professors Harry Noller, Bill Scott, Melissa Jurica and Seth Rubin (Dept. of
MCD Biology, Dept. of Chemistry and Biochemistry). UCSC scientists have used
the facility to investigate the structure of the ribosome, catalytic RNA ("ribozymes"), the spliceosome, and
protein structures relevant to cell cycle regulation. Users of the facility
also collaborate with the Lawrence Berkeley National Laboratory's Advanced Light
Source synchrotron radiation facility and the Stanford Synchrotron Light Source. |
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